منابع مشابه
the relationship between eq, iq and test format: a study on test fairness
the major aim of this study was to investigate the relationship between iq, eq and test format in the light of test fairness considerations. this study took this relationship into account to see if people with different eq and iq performed differently on different test formats. to this end, 90 advanced learners of english form college of ferdowsi university of mashhad were chosen. they were ask...
15 صفحه اولFolding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain.
The mouse TSH receptor ectodomain (mTSHR-ecd) was amplified from murine thyroid complementary DNA and ligated into the pAcGP67B insect cell vector, and the nucleotide sequence was confirmed. Employing a baculovirus-insect cell system, the mTSHR-ecd (amino acids 22-415) was expressed as a fusion protein with the gp67 insect cell signal sequence at the NH2-terminus and a C-terminal six-histidine ...
متن کاملResistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
Resistance to TSH (RTSH) is a recently described syndrome of reduced sensitivity to TSH that manifests as euthyroid hyperthyrotropinemia. It is usually identified at birth during routine neonatal screening for congenital hypothyroidism. In less than 2 yr, 13 subjects with RTSH belonging to 8 families have been reported, and all were shown to harbor mutations in the TSH receptor (TSHR) gene. We ...
متن کاملTwo novel mutations in the thyrotropin (TSH) receptor gene in a child with resistance to TSH.
The TSH receptor is a G protein-coupled receptor that mediates the effects of TSH in thyroid development, growth, and synthetic function. We report here that a child with features of TSH resistance, including markedly increased serum TSH concentrations and low normal thyroid hormone levels, is a compound heterozygote for two novel mutations in the TSH receptor gene. One allele has a G to A tran...
متن کاملTSH screening
That means there is considerable overlap in what we would consider the true euthyroid state in a patient. Hence, a population may be well characterised by this screening process, but it doesn't closely reflect the individual situation. As a result, an abnormal result of the population-based screening should not necessarily translate into an automatic decision on the requirement of treatment. Th...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1976
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.25.12_818